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LIFTT operates as an active venture capital firm, specializing in early-stage deep tech investments. Its primary offering involves providing capital alongside substantial operational support to startups, focusing on critical resources, human health, and energy sectors. The firm employs a rigorous selection process, coupled with hands-on growth assistance, managerial coaching, and strategic guidance for its portfolio companies.
The firm was founded in 2019, chaired by Stefano Buono, a nuclear physicist and successful entrepreneur with prior experience founding Advanced Accelerator Applications. The foundational insight behind LIFTT was to leverage deep technical expertise and an entrepreneurial approach to actively support innovators, fostering growth beyond mere financial injection.
LIFTT serves innovative startups seeking both capital and strategic guidance to scale their transformative technologies. The company’s vision is to anticipate future needs by investing in enabling technologies, aiming to build a more regenerative and resilient economy. It supports ventures developing scalable solutions to address systemic global challenges.
Key people at LIFTT.
Key people at LIFTT.
LIFTT is an Italian venture capital (VC) holding company founded in 2020 that focuses on investing in cutting-edge, disruptive deep tech startups across various sectors without strict vertical limitations. It has raised over €100 million and invested in more than 50 startups globally, primarily at early stages from idea or patent through scaling. LIFTT targets breakthrough technologies in hardware B2B deep tech fields such as energy, quantum computing, photonics, semiconductors, and advanced materials, emphasizing unique intellectual property and exceptional scientific teams. The firm provides patient capital combined with a hands-on, active support approach, leveraging a team of 27 professionals and a network of over 200 shareholders to assist portfolio companies in their growth phases[1][2][6].
LIFTT was established in mid-2020, co-founded by the Politecnico di Torino and Compagnia di San Paolo, Italy’s largest banking foundation, with Stefano Buono, a physicist turned entrepreneur, serving as Chairman. The firm emerged to address the financing gap for innovative, high-growth startups in Italy and Europe, particularly in deep tech sectors. Since inception, LIFTT has evolved to raise significant capital (over €115 million) and build a portfolio exceeding 56 companies, focusing on fostering technology transfer and innovation within Italy and beyond. Its founding vision integrates an ethical business model inspired by ESG principles and a commitment to supporting startups through direct involvement and strategic guidance[2][4][6].
LIFTT rides the global trend of deep tech innovation, focusing on hardware and scientific breakthroughs that require long-term patient capital and specialized support. The timing is critical as Europe and Italy seek to strengthen their technology sovereignty and innovation capacity amid global competition. Market forces such as increased demand for sustainable energy solutions, quantum technologies, and advanced materials favor LIFTT’s investment thesis. By bridging the gap between scientific research and commercialization, LIFTT influences the broader ecosystem by nurturing startups that contribute to regional economic growth and technological leadership. Its collaboration with European institutions and alignment with ESG principles further embed it within the evolving landscape of responsible innovation financing[3][4][5].
Looking ahead, LIFTT is positioned to expand its portfolio and deepen its impact on the European deep tech ecosystem, supported by ongoing capital raises targeting €90 million by 2024 and partnerships with major foundations and asset managers. Trends such as the acceleration of quantum computing, cleantech adoption, and AI integration will shape its investment focus. LIFTT’s hands-on, patient capital approach combined with its strong network and ethical framework suggests it will continue to be a key player in transforming early-stage scientific innovations into scalable businesses, potentially influencing policy and investment norms in the European venture capital space. Its evolution will likely reinforce Italy’s role as a hub for deep tech innovation and sustainable technology transfer[4][5][6].
LIFTT has 13 tracked investments across 10 companies. The latest tracked deal is $31.9M Series A in Sparrow Quantum in December 2025.