Amplitude Ventures

High-Level Overview

Amplitude Ventures is a Montreal-based venture capital firm founded in 2018, specializing in healthcare investments, particularly precision medicine at the intersection of biology and AI, as well as next-generation medical devices.[1][2][4][5] Its mission is to act as a "capital catalyst" for Canada's most promising healthcare companies at the value acceleration stage, deploying a venture growth model to build world-class firms with strong management teams and scale them to breakout potential, evidenced by over $1 billion in prior company value created since 2012.[1][4] The firm manages over $500 million in assets, with offices in Montreal, Toronto, Vancouver, and Calgary, and focuses on therapeutics, medical technologies, AI-enabled precision medicine, healthcare IT, and services.[2][3][4] Amplitude impacts the startup ecosystem by providing hands-on support, fostering outcomes for founders, patients, and investors—having scaled companies, supported approved products, and addressed patient needs—while partnering with entrepreneurs to advance groundbreaking technologies.[1][4]

Origin Story

Amplitude Ventures emerged in 2018 as a spinoff from BDC Capital, launched by departing partners Dion Madsen and Jean-François Pariseau, who brought deep experience in Canadian healthcare investing.[2][3] The team's roots trace back to 2012, when they began deploying a proven venture growth model to create, build, and scale healthcare companies, amassing over $1 billion in value.[1] Key partners today include Dion Madsen (Partner, Montreal), Dr. Ali Tehrani (Partner, Vancouver), Allison Gaw (Principal, Vancouver), and Bharat Srinivasa (Principal, Toronto).[6] The firm's focus has evolved from broad healthcare innovation to a sharpened emphasis on precision medicine and AI-biology intersections, maintaining a Canada-centric geographic strategy while building global-scale companies.[1][3][4]

Core Differentiators

• Unique Investment Model: Applies an evidence-based, full-stack venture growth approach—beyond capital, it builds management teams, accelerates value, and provides tactical/strategic support, drawing from a track record of scaling companies and $1B+ in value creation.[1][4]
• Network Strength: Strong North American connections, evidenced by founder testimonials praising introductions to investors, partners, talent, and ecosystem players; acts as a "thought partner" from early stages through exits like acquisitions.[4]
• Track Record: Has supported companies to product approvals, scaled operations, and impacted patients; closed two funds (one in Jun 2021, another in May 2024); backed firms like Ability, Congruence, and Abdera.[4][6]
• Operating Support: Domain expertise in biotech, honesty, transparency, and active involvement (e.g., board roles, financing leadership), prioritizing founder success and patient outcomes.[1][4]

Role in the Broader Tech Landscape

Amplitude Ventures rides the precision medicine wave, capitalizing on AI's convergence with biology to enable personalized therapeutics, diagnostics, and devices amid rising demand for efficient healthcare solutions.[1][4] Timing is ideal post-2018 launch, aligning with AI breakthroughs in protein folding and data-driven drug discovery, plus post-pandemic emphasis on innovative medtech.[3][4] Favorable market forces include Canada's talent pool in AI/healthcare, government support for life sciences, and global healthcare spending growth, positioning Amplitude to scale domestic startups internationally against giants like OrbiMed or Sequoia.[2] It influences the ecosystem by bridging Canadian innovation to U.S. markets, fostering AI-enabled precision medicine, and demonstrating VC models that prioritize patient impact over pure financial returns.[1][3][4]

Quick Take & Future Outlook

Amplitude Ventures is poised to lead Canada's precision medicine surge, likely raising Fund III post-2024 closes to back AI-biology hybrids amid exploding demand for targeted therapies and diagnostics.[4][6] Trends like multimodal AI models, regulatory tailwinds for digital health, and cross-border M&A will shape its path, amplifying influence through more scaled exits and ecosystem hubs in its office cities.[1][2] As a catalyst since 2012, expect it to evolve from value-builder to global healthcare powerhouse, sustaining its edge in founder-centric, outcome-focused investing.[1][4]