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§ Private Profile · Cambridge, MA, USA
Using the immune system to cure disease
Parallel Bio has raised $25.0M across 2 funding rounds.
Key people at Parallel Bio.
Parallel Bio was founded in 2021 by Juliana Hilliard (Founder) and Robert DiFazio (Founder).
Parallel Bio has raised $25.0M in total across 2 funding rounds.
Parallel Bio created a human 'immune system in a dish' to discover drugs and immunotherapies more likely to work in patients. Our platform has all of the same elements as a human immune system, meaning you can test drugs and vaccines as if you were testing them in actual patients from the start. The biggest reason why 95% of new drugs fail is that they were tested in mice - but with our human platform, pharma companies will know which drugs will successfully treat patients, speeding up the process and reducing the cost. To date our platform has successfully been used to test 12 drugs, and vaccines against 8 different diseases. The company is founded by Robert DiFazio, a former Stanford R&D director with a PhD in immunology, and Juliana Hilliard, a former System1 Biosciences R&D lead with an MSc in bioengineering, both of whom have led drug discovery programs for years.
Parallel Bio is a pioneering biotechnology company focused on revolutionizing drug discovery and development by harnessing the human immune system. It uses a unique platform that combines immune organoids—miniature, lab-grown models of the human immune system—and artificial intelligence (AI) to design and test therapies that work in humans from the start, bypassing many traditional clinical trial hurdles. This approach aims to make drug development safer, faster, and more cost-effective by reducing reliance on animal testing and improving prediction of drug safety and efficacy across diverse human populations. Parallel Bio primarily serves pharmaceutical and biotech companies by providing a "clinical trial in a dish" platform that models human immune responses more realistically than animal models, accelerating the path to effective immunotherapies for diseases such as cancer, autoimmune disorders, and infectious diseases[1][2][3][7].
Parallel Bio was founded in 2020 (or 2021, according to some sources) by scientists Juliana Hilliard and Robert DiFazio, who developed the world’s first scalable human immune organoid. The idea emerged during the COVID-19 pandemic to address a critical gap in disease modeling and drug discovery. They recognized the immune system as the master regulator of health and disease and sought to create a platform that replicates the human immune system's complexity outside the body. Early traction included testing 12 drugs and vaccines against eight diseases using their immune system model and securing partnerships with major pharmaceutical companies, including Fortune 500 firms. The company has evolved from proving its core technology to scaling its platform to work with many partners and drug pipelines[2][4][7].
Parallel Bio rides the growing trend of human-first drug discovery and immunotherapy development, which are reshaping medicine by targeting the immune system to treat a wide range of diseases. The timing is critical as regulatory agencies like the FDA are moving toward reducing animal testing requirements, creating a favorable environment for human-based models. Market forces such as the high failure rate of drugs in clinical trials, rising R&D costs, and demand for personalized medicine further support Parallel Bio’s approach. By providing a scalable, AI-driven immune organoid platform, Parallel Bio influences the biotech ecosystem by enabling faster, safer, and more inclusive drug development, potentially transforming how therapies are designed and validated globally[1][2][7].
Parallel Bio is positioned to significantly disrupt traditional drug development by advancing its immune organoid platform and expanding partnerships with pharmaceutical companies. Future trends shaping its journey include increased regulatory acceptance of human-based models, advances in AI and organoid technology, and growing demand for precision immunotherapies. The company’s influence is likely to grow as it moves from validating its platform with partners to developing proprietary drug candidates in-house. This evolution could accelerate the delivery of safer, more effective therapies to diverse patient populations worldwide, fulfilling its mission to unlock the immune system’s power to cure disease without the traditional risks and costs of clinical trials[7][8].
Parallel Bio was founded in 2021 by Juliana Hilliard (Founder) and Robert DiFazio (Founder).
Parallel Bio has raised $25.0M in total across 2 funding rounds.
Parallel Bio's investors include Krish Ramadurai, ACME Capital, Frederique Dame, Harmonix Fund, IVP, Hans Tung, Seven Seven Six, The General Partnership, The House Fund, Ulu Ventures, Workday Ventures, Arash Ferdowsi.
Key people at Parallel Bio.
Parallel Bio has raised $25.0M across 2 funding rounds. Most recently, it raised $21.0M Series A in June 2025.
| Date | Round | Lead Investors | Other Investors | Status |
|---|---|---|---|---|
| Jun 1, 2025 | $21M Series A | Krish Ramadurai | ACME Capital, Frederique Dame, Harmonix Fund, IVP, Hans Tung, Seven Seven SIX, The General Partnership, The House Fund, ULU Ventures, Workday Ventures, Arash Ferdowsi, Ding Zhou, Gokul Rajaram, Kevin Weil, Amplo, Jeff Dean, Marc Benioff, Atypical Ventures, Humba Ventures, Metaplanet, Undeterred Capital | Announced |
| Dec 1, 2022 | $4M Seed | Refactor Capital | Atomic, Eclipse Ventures, Greenoaks Capital, Humba Ventures, Incite Ventures, Mayfield, Offline Ventures, SV Angel, Y Combinator, SAM Altman, Jeff Dean, Breakout Ventures, Testmunk | Announced |