Deep Principle

Deep Principle is a Hangzhou, China-based technology company that develops artificial intelligence platforms to accelerate materials discovery and chemical innovation. The organization utilizes proprietary systems to facilitate autonomous molecular design, reaction prediction, and high-throughput experimentation across the fine chemicals, catalytic materials, and energy sectors. The enterprise has secured over RMB 10 million in commercial contracts, providing research and development software to corporate clients such as L'Oréal and Sunsea Innovation. In November 2025, the company raised over RMB 100 million in a Series A funding round co-led by Alibaba Entrepreneurs Fund and Ant Group, following earlier seed investments from Hillhouse Ventures and Baidu Ventures. The firm has also published its generative artificial intelligence models in peer-reviewed scientific journals including Nature Computational Science. Deep Principle was founded in 2024 by Duan Chenru and Dr. Jia Haojun.