3x5 Partners

3x5 Partners was a venture capital firm focused on identifying and investing in early to growth-stage companies within the life science and natural resource sectors. The firm’s core approach involved supporting ventures that developed solutions to pressing global challenges in health and climate, specifically across critical areas such as energy, food systems, and healthcare innovation. Its investment thesis centered on the belief that scientific and technological advancements could drive both economic growth and societal benefit.

The firm was founded in 2011 by Tony Arnerich and other partners, stemming from a collective insight into the growing need for capital directed towards impactful solutions. The founders established 3x5 Partners with a clear mandate: to collaborate with entrepreneurs dedicated to delivering advancements in fundamental human needs like health, clean resources, and sustainable infrastructure. This foundational principle guided their investment decisions and portfolio construction.

3x5 Partners cultivated a portfolio of companies, partnering closely with founders to scale their innovations and realize their potential. The firm’s enduring vision was to achieve a dual outcome of generating strong returns for investors while fostering positive global impact through its portfolio companies. This strategic focus ultimately led to its venture capital team integrating with American Century Investments, continuing its mission under a larger platform.